Nov. 29, 2019 Updated

Nanomedicine has high potential for early detection of disorders and achieving unprecedented treatment efficacies, even against intractable diseases, by effectively overcoming biological barriers and controlling the function of bioactive agents in the body. In our group, we aim to develop nanomedicines for effective diagnosis and therapy through the precise sensing of targets in the body and the triggering of the nanomedicines' activity at specific sites, modulating the behavior of the loaded drugs, even at the subcellular level.

The aspects involved in the design of successful nanomedicines and the interplay of nanomedicines with the biological interface are major interests of the lab, focusing on the ultimate translation of nanomedicine strategies to humans.

The University of Tokyo, Department of Bioengineering
Bld.#5 , 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656 (MAP)

What's new
Ms. Noriko Nakamura (D2) received the JSB Outstanding Poster Award 2019 at the 41st Annual Meeting of the Japanese Society for Biomaterials (Ibaraki, Japan). The presentation title is "Interaction analysis between target membrane proteins and ligand molecules attached to the polymeric micelle with different molecular weight of hydrophilic shell" (Coauthers: Yasutaka Anraku, Shigeto Fukushima, Kazuko Tou, Horacio Cabral, Kazunori Kataoka).
Mr. Eger Boonstra received the "Young Researchers Poster Award" at the 4th International Symposium on Biomedical Engineering, ISBE 2019 in Hamamatsu, Japan for his work "Mechanistic analyses of polymer/lipid-based gene transfection processes through membrane integrity assay using proton sensing transistor" (co-authors: Hiroaki Hatano, Tatsuro Goda, Satoshi Uchida, Horacio Cabral and Yuji Miyahara).
Ms. Thahomina Khan received the "Young Authors Travel Award" at the 32nd International Microprocesses and Nanotechnology Conference, MNC 2019. Hiroshima, Japan for her work "Development of polymeric micelles with 5-Boronopicolinic acid ligand to target sialylated epitopes in intratumoral microenvironment" (co-auhtors: Kazunori Igarashi, Akira Matsumoto, Horacio Cabral and Kazunori Kataoka).
Dr. Yasutaka Anraku (Associate Professor) was introduced in the JSTnews October issue "Leading Scientist" corner of the Japan Science and Technology Agency (JST).
Dr. Yasutaka Anraku (Associate Professor) received KATSUSHI Award (Research).
This award is an honorable award given to two young faculty members (under 45 years) from the Graduate School of Engineering, The University of Tokyo.