Nanomedicine has high potential for early detection of disorders and achieving unprecedented treatment efficacies, even against intractable diseases, by effectively overcoming biological barriers and controlling the function of bioactive agents in the body. In our group, we aim to develop nanomedicines for effective diagnosis and therapy through the precise sensing of targets in the body and the triggering of the nanomedicines' activity at specific sites, modulating the behavior of the loaded drugs, even at the subcellular level.
The aspects involved in the design of successful nanomedicines and the interplay of nanomedicines with the biological interface are major interests of the lab, focusing on the ultimate translation of nanomedicine strategies to humans.
The University of Tokyo, Department of Bioengineering
Bld.#5 , 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656 (MAP)
- 12/10/2022
- Horacio CABRAL Associate Professor entitled "Polymeric micelles effectively reprogram the tumor microenvironment to potentiate nano-immunotherapy in mouse breast cancer models" has been published on Nature Communications.
▶ (12/14)Investigación y Ciencia
▶ (12/07)The University of Tokyo Press Release
▶ (12/06)EurekAlert!
▶ (12/06)PHYS-ORG News
▶ (12/06)Today's Chronic - 04/21/2022
- Dr. Wenqian Yang has been awarded the postdoctoral fellowship from the Chugai Foundation for Innovative Drug Discovery Science.
- 11/15/2021
- Associate Professor Yasutaka Anraku appeared on NHK BS1 Special.
▶ BS1 Special Program Site (Japanese) - 07/27/2021
- Associate Professor Yasutaka Anraku appeared on NHK World’s“Medical Frontiers”. The program can be viewed on NHK On Demand.
▶ Medical Frontiers -Tackling Dementia After Onset- - 03/10/2021
- Dr. Takuya Miyazaki (visiting researcher) received "Presentation Award" for our work "Development of polymeric micelles for safe and effective delivery of therapeutic protein" at the final presentation in NEDO Technology Commercialization Program (TCP).
- 03/10/2021
- Dr. Takuya Miyazaki (visiting researcher) received "Venture Capital Award" for our work "Development of polymeric micelles for safe and effective delivery of therapeutic protein" at the final presentation in NEDO Technology Commercialization Program (TCP).
- 03/10/2021
- Dr. Takuya Miyazaki (visiting researcher) received "Japan Science and Technology Agency (JST) Award" for our work "Development of polymeric micelles for safe and effective delivery of therapeutic protein" at the final presentation in NEDO Technology Commercialization Program (TCP).
- 11/18/2020
- Dr. Satoshi Uchida (visiting researcher) received "1st Poster Award" at the 8th International mRNA Health Conference (Online) for his work "mRNA bundling inside polyion complexes for their physical and biological stabilization" (Co-authors: Kyoko Koji, Naoto Yoshinaga, Yuki Mochida, Taehun Hong, Horacio Cabral)
- 10/13/2020
- The article "Nanomedicine-Based Approaches for mRNA Delivery" published in Molecular Pharmaceutics on October 5th was adopted as the cover page (Co-authors: S. Uchida, F. Perche, C. Pichon, H. Cabral)
▶ Nanomedicine-based approaches for mRNA delivery. - 08/25/2020
- The article "Polymeric Nanocarriers with Controlled Chain Flexibility Boost mRNA Delivery In Vivo through Enhanced Structural Fastening" published in Advanced Healthcare Materials on June 25 was adopted as the cover page (Authors: Takuya Miyazaki, Satoshi Uchida, Satoru Nagatoishi , Kyoko Koji, Taehun Hong, Shigeto Fukushima, Kohei Tsumoto, Kazuhiko Ishihara, Kazunori Kataoka, Horacio Cabral).
▶ Inside Back Cover - 04/10/2020
- Dr. Takuya Miyazaki (visiting researcher) received "Public Releations Committee Publicity Award" at the 69th Polymer Conference in Fukuoka, Japan for his work "Development of size-tuned polymeric micelles for safe and efficient chemotherapy during pregnancy" (Co-authors: Kensuke Suzuki, Takeshi Nagamatsu, Kazunori Kataoka, Horacio Cabral)
- 04/02/2020
- Our paper entitled "A chemically unmodified agonistic DNA with growth factor functionality for in vivo therapeutic application" has been published online in Science Advances.
▶ A chemically unmodified agonistic DNA with growth factor functionality for in vivo therapeutic application.
▶ School of Engineering The University of Tokyo Press Releases