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Graduation ceremony on Mar 21st
In this semester, Li Shang-Wei and Lucas Mixich have graduated from their PhD programs. Congratulations to Dr. Li and Dr. Lucas!
Selective Intracellular Delivery of Antibodies in Cancer Cells with Nanocarriers Sensing Endo/Lysosomal Enzymatic Activity
Pengwen Chen, Wenqian Yang, Yuki Mochida, Shangwei Li, Taehun Hong, Hiroaki Kinoh, Kazunori Kataoka, Horacio Cabral Angew. Chem. Int. Ed. 2024, e202317817. (DOI:10.1002/anie.202317817) Selective Intracellular Delivery of Antibodies in Cancer Cells with Nanocarriers Sensing Endo/Lysosomal Enzymatic Activity Abstract: The differential enzymatic activity in the endo/lysosomes of particular cells could trigger targeted endosomal escape functions, enabling…
Nanoassemblies of heptamethine cyanine dye-initiated poly(amino acid) enhance ROS generation for effective antitumour phototherapy
Pengwen Chen, Shangwei Li, Zhining Xu, Horacio Cabral Nanoscale Horiz., 2024, Advance Article (DOI:10.1039/D3NH00584D)Nanoassemblies of heptamethine cyanine dye-initiated poly(amino acid) enhance ROS generation for effective antitumour phototherapy Abstract: Phototherapy shows great potential for pinpoint tumour treatment. Heptamethine cyanine dyes like IR783 have high potential as agents for antitumour phototherapy due to their inherent tumour targeting…
Nanocarriers address intracellular barriers for efficient drug delivery, overcoming drug resistance, subcellular targeting and controlled release
Jing Liu, Horacio Cabral, Peng Mi Adv. Drug Deliv. Rev., 115239 (2024) (DOI:10.1016/j.addr.2024.115239) Nanocarriers address intracellular barriers for efficient drug delivery, overcoming drug resistance, subcellular targeting and controlled release Abstract: The cellular barriers are major bottlenecks for bioactive compounds entering into cells to accomplish their biological functions, which limits their biomedical applications. Nanocarriers have demonstrated high potential and benefits for encapsulating bioactive…